Diazoxide and hypotension.

Hypotension in Reconstructive and Plastic Surgery

to 60m.m.Hg. and with no ill effects at the end of the anaesthesia and the tremination of the operation the drops of the serum which contains 15mg. Wyamin will be in­creased to rise the blood pressure, now if the anaesthetic drug is Halothane recovery is quick and if Ether is used it is a little pro­longed. If while operating there is need for further injection of Adrenaline solution in the ope...

Diazoxide in von Gierke's disease.

Leucine-sensitive hypoglycaemia treated with diazoxide.

It has been estimated that about one-third of children with so-called idiopathic hypoglycaemia are leucine sensitive (Mabry, Di George, and Auerbach, 1960). However, the total number of leucine-sensitive cases reported is still relatively small. In 1960, Di George and Auerbach knew of no more than 30 cases and only a few have been reported since then. We therefore describe two further cases, on...

Diazoxide in treatment of primary pulmonary hypertension.

Three patients with primary pulmonary hypertension and one man with suspected thromboembolic pulmonary hypertension were given up to 300 mg diazoxide by injection into the pulmonary artery. The three patients with primary pulmonary hypertension responded with a fall in total pulmonary resistance and a rise in cardiac output. The patient with suspected thromboembolic pulmonary hypertension did n...

Effects of diazoxide in multiple sclerosis

Objective: The aim of this study was to test the safety of diazoxide and to search for signs of efficacy in patients with relapsing-remitting multiple sclerosis (RRMS). Methods: In this multicenter, randomized, placebo-controlled, double-blind trial (treatment allocation was concealed), 102 patients with RRMS were randomized to receive a daily oral dose of diazoxide (0.3 and 4 mg/d) or placebo ...